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Ding a lengthy disease duration that's often related using the subtle onset of clinical symptoms (Leinenga et al., 2016). That is also reflected by a paucity of animal models that reproduce the complexity of these situations (Ittner et al., 2015). A popular hallmark of tauopathies (for instance AD in addition to a major subset of FTLD termed FTLD-tau) may be the pathological intracellular accumula
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